Looking for the best slice of life anime that blends heartwarming stories, everyday moments, and gentle humor? Whether you’re a longtime fan or just starting your anime journey, these shows perfectly capture the charm of ordinary life.
From slow-burn romances to laugh-out-loud romantic comedy anime, each series on this list delivers wholesome entertainment and relatable characters. If you’re in the mood for wholesome anime that makes you smile, relax, and even shed a happy tear, this handpicked Part 2 guide is your perfect watchlist.
Let’s start the article
My Senpai Is Annoying – A Wholesome Romantic Comedy Anime

Studio: Doga Kobo
Aired: October – December 2021
Episodes: 12
Summary: Futaba Igarashi is a hardworking but petite office lady who struggles to be taken seriously at her job. Her towering senior, Harumi Takeda, is always teasing her while also watching her back, making her feel both irritated and oddly protected. From late-night work sessions to after-office drinks, their relationship slowly shifts from playful annoyance to subtle affection. Side characters like Sakurai and Kazama add their own sweet chemistry, creating a lively workplace filled with warm friendships and budding romances.
Why Watch: If you enjoy romantic comedy anime with relatable workplace humor and adorable chemistry, this is a must-watch. The gentle mix of comedy and heartwarming moments makes it perfect for fans of wholesome anime.
Senryu Girl – Best Slice of Life Anime About Poetic Love

Studio: Connect
Aired: April – June 2019
Episodes: 12
Summary: Nanako Yukishiro speaks only through senryu, short Japanese poems, making her communication style unique and charming. When she joins the school’s Literature Club, she meets Eiji Busujima, a misunderstood ex-delinquent with a soft heart. Together, they express feelings through poetry, creating quiet yet meaningful interactions. Each episode blends gentle humor and heartfelt moments, exploring how friendship and love can flourish without spoken words.
Why Watch: This wholesome anime proves that emotions can be conveyed in the simplest ways. With its romantic comedy elements and poetic charm, Senryu Girl is short, sweet, and perfect for fans who love soft, relaxing stories.
Uzaki-chan Wants to Hang Out! – A Fun and Wholesome College Comedy

Studio: ENGI
Aired: Season 1: July – September 2020; Season 2: October – December 2022
Episodes: 12 (S1) + 13 (S2)
Summary: College student Shinichi Sakurai dreams of a peaceful life, but his underclassman Hana Uzaki has other plans. Loud, playful, and full of energy, Uzaki constantly drags Shinichi into social adventures—be it gaming, café hopping, or spontaneous trips. Their endless teasing and back-and-forth banter create hilarious misunderstandings, while deeper feelings slowly develop beneath the comedy. Season two even explores their growing awareness of each other, adding a subtle romantic layer to their antics.
Why Watch: For fans of romantic comedy anime with a lively and mischievous heroine, Uzaki-chan offers laugh-out-loud humor balanced with moments of unexpected warmth.
When Will Ayumu Make His Move? – Cute Slice of Life Romance Anime

Studio: Silver Link
Aired: July – September 2022
Episodes: 12
Summary: Ayumu Tanaka is determined to confess his love to his senpai, Urushi Yaotome—but only after he can finally beat her in a game of shogi. The catch? Urushi is far more skilled, and Ayumu keeps losing. Their daily matches are filled with deadpan humor, subtle flirting, and clever shogi strategies. As they spend more time together, their bond deepens beyond the game board, while their friends cheer (and tease) them along the way.
Why Watch: This wholesome anime perfectly blends the tension of unspoken feelings with the slow burn of a romantic comedy. It’s clever, cute, and ideal for viewers who enjoy gentle slice of life romance.
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Aharen-san Is Indecipherable – Quirky and Wholesome Anime Comedy

Studio: Felix Film
Aired: April – June 2022
Episodes: 12
Summary: Reina Aharen is a quiet high school girl who struggles with personal space and communication. Her classmate Raido, curious about her unpredictable behavior, slowly becomes her closest friend. Whether it’s epic misunderstandings, over-the-top gestures, or absurdly creative bonding activities, their friendship blossoms into something beautifully unique. Their classmates join in the fun, turning every episode into a mix of ridiculous comedy and soft-hearted moments.
Why Watch: With its offbeat humor and surprisingly tender character growth, Aharen-san is a hidden gem among wholesome slice of life anime.
Tsukigakirei – Heartwarming First Love Slice of Life Anime

Studio: feel.
Aired: April – June 2017
Episodes: 12
Summary: Middle school students Akane Mizuno and Kotarou Azumi experience the awkward magic of first love. From shy text messages to quiet walks home after school, their relationship grows with an authenticity rarely seen in anime. As they navigate family expectations and personal dreams, the series captures the bittersweet excitement of young romance with breathtaking realism. The soft animation style and heartfelt soundtrack enhance every moment.
Why Watch: If you’re searching for a wholesome anime that perfectly portrays the tender emotions of first love, Tsukigakirei is an unforgettable masterpiece.
Tsuredure Children – Romantic Comedy Anime with Multiple Couples

Studio: Studio Gokumi
Aired: July – September 2017
Episodes: 12
Summary: Tsuredure Children is a delightful anthology of short love stories featuring multiple high school couples. From shy confessions to comedic misunderstandings, each pair explores a different side of teenage romance. Whether it’s the quiet charm of first love or the chaotic energy of bold declarations, every segment offers something fresh and heartwarming.
Why Watch: Perfect for viewers who love variety, this romantic comedy anime showcases many lovable characters and entertaining scenarios in bite-sized episodes.
Monthly Girls’ Nozaki-kun – Comedy Gold for Shoujo and Slice of Life Fans

Studio: Doga Kobo
Aired: July – September 2014
Episodes: 12
Summary: High schooler Chiyo Sakura gathers the courage to confess her feelings to her crush, Umetarou Nozaki. But instead of understanding her confession, Nozaki—secretly a famous shoujo manga artist—mistakes her as a fan and recruits her as his manga assistant. Chiyo soon finds herself in hilarious situations with Nozaki’s eccentric friends while also learning the unpredictable world of shoujo manga creation. Their dynamic blends meta-humor with slow-burn affection.
Why Watch: For anyone who enjoys romantic comedy anime that playfully mocks shoujo clichés while delivering genuine laughs, Monthly Girls’ Nozaki-kun is pure gold.
Teasing Master Takagi-san – The Ultimate Wholesome Slice of Life Anime

Studio: Shin-Ei Animation
Aired: Season 1: January – March 2018 (with later seasons and a movie)
Episodes: 12 (S1)
Summary: Nishikata spends his school days trying to one-up his classmate Takagi, who delights in teasing him. No matter how clever his pranks, Takagi always outsmarts him with effortless charm. Their playful rivalry slowly evolves into a heartwarming bond as both grow closer, revealing subtle hints of budding romance. Each episode delivers a perfect mix of lighthearted humor and soft emotional moments.
Why Watch: With its gentle comedy and sweet romantic undertones, this wholesome anime is the perfect feel-good watch for all ages.
The Pet Girl of Sakurasou – Heartfelt Romantic Comedy Anime

Studio: J.C. Staff
Aired: October 2012 – March 2013
Episodes: 24
Summary: Sorata Kanda moves into Sakura Hall, a dorm known for its eccentric residents. Among them is Mashiro Shiina, a world-class artist with no sense of daily life skills. Tasked with looking after Mashiro, Sorata finds himself surrounded by quirky classmates—each with dreams and insecurities of their own. Their journey explores ambition, failure, friendship, and love, making this series far more than just a romantic comedy. The emotional highs and lows will stay with you long after the finale.
Why Watch: A perfect blend of comedy, drama, and inspiration, The Pet Girl of Sakurasou stands out as one of the best slice of life anime with a powerful message about pursuing dreams.
Final Thoughts on the Best Slice of Life Anime (Part 2)
These ten titles perfectly capture why best slice of life anime remains one of the most beloved genres: relatable characters, heartwarming relationships, and stories that turn ordinary moments into something extraordinary. Whether you want a romantic comedy anime to make you laugh or a wholesome anime to warm your heart, this list has your next favorite show.
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